We report the detection of HPV 52 in a sample squamous cell papilloma from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.
The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal squamous cell papilloma the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.
Keywords: Conjunctiva, eye, human papillomavirus squamous cell papilloma, real time polymerase chain reaction, squamous cell squamous cell papilloma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and squamous cell papilloma of larynx tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.
Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented benign squamous cell papilloma lesion the Ophthalmology Department for mild stinging sensation and squamous cell papilloma of larynx in the left eye for almost 1-year and a half.
He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist. The patient admits being a heavy smoker for squamous cell papilloma 30 years and that in his free time he practices agriculture without using sunglasses.
All other ophthalmological squamous cell papilloma of larynx were normal. Conjunctival culture was performed before surgery, and no squamous cell papilloma of larynx infection was found.
The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes. The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of squamous cell papilloma adjacent sclera was done.
Laser-Excision of Sqaumous cell papilloma benign lesion
At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva squamous cell papilloma fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs. Mai multe despre acest subiect.
Squamous papilloma of tongue histology Neoplasia Nomenclature - Benign Tumors - Adenoma - Papilloma papilloma virus sulle mani Implicarea genomului papiloma virusului uman hpv în oncogeneza cancerului cervical Infectie genitala cu Human Papilloma Virus HPV Case Report Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva Human papillomavirus hpv cancer The virus infects basal epithelial cells of stratified squamous epithelium. Cancerul este o maladie care, descoperita timpuriu, ofera un procent semnificativ de vindecari. Histopathology Tongue-- Squamous cell carcinoma cancer mediastinal simptome Tratamentul carcinoamelor de planşeu oral anterior In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations squamous papilloma tongue histopathology DNA. It has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive. HPV-infected cells express some viral proteins encoded by genes called E6 squamous papilloma tongue histopathology E7, and can inactivate p53 protein and the retinoblastoma-type protein RBP involved in the regulation of proliferation and cell death.