Colorectal cancer who 2020. UGR scientists patent an effective drug for treating breast, colon, and skin cancers

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The researchers have proved the anti-tumor effects of the drug on immunodeficient mice. The new compound and its derivatives enabled the researchers to reduce tumor activity by 50 percent after 41 days of treatment with the drugadministered twice a week, to mice with induced tumors.

CHIRURGIA ROBOTICA pentru cancerul colo-rectal

They have also managed to successfully describe the mechanisms by which the drug acts on the cancer stem cells CSCs. The Córdoba-based company Canvax Biotech has also participated in the development of the patent. A non-toxic drug One of the major advantages of the drug is that it is non-toxic.

colorectal cancer who 2020

Despite being administered to the mice in high concentrations milligrams per kilono adverse effects were observed in the healthy cells.

Moreover, colorectal cancer who 2020 a pharmaceutical perspective this anti-tumor drug can be successfully produced in large quantities. The researchers were able to obtain the required amount of the synthesis in just five days. In the initial phases of their research, the scientists had already managed to create an effective drug called Bozepinib for treating cancer stem cellsbut the process involved in its chemical synthesis was lengthy and required a great deal of time to produce very small quantities of the drug.

Death rates from pancreatic cancer predicted to rise in Europe in 2014

Having completed structural modifications of the drug—Bozepinib by making changes to its molecular architecturethey have successfully created a compound which maintains the biological activity of its predecessor as an effective anti-tumor drug, but which can also be synthesized and produced colorectal cancer who 2020 a grand scale—a fundamental condition for the drug's commercial development.

In order to be able to test the new drug on mice and gauge its effectiveness on human tumors, first of all they had to inject human tumor cells into immunodeficient mice to ensure they did not reject these cancerous cells.

Following the treatment, they discovered that some of the compounds effectively inhibited the growth of the tumor cells and the migration ability of these cells to other healthy tissues, considerably diminishing the likelihood of metastasis.

The drug directly targets CSCs without affecting the healthy cellsa huge advantagewhen compared to other cancer treatments such as chemotherapy.

Death rates from pancreatic cancer predicted to rise in Europe in Rates for all other cancers, except female lung cancer, continue to fall European Society for Medical Oncology Print  E-Mail Pancreatic cancer is the only cancer for which deaths are predicted to increase in men and women rather than decrease in and beyond, according to a comprehensive study published in the leading cancer journal Annals of Oncology [1] today Thursday. The study by researchers in Italy and Switzerland shows that the proportion of deaths due to any sort of cancer is expected to fall overall in Europe in

AlthoughCSCs are only found oxiuros informacion small quantities in tumors, from a clinical perspective the ability to target them directly is of fundamental importance, given that they are responsible for originally causing the tumor, relapses and resistance to anticancer treatments. The next step: Lungs and pancreas Having proved the pre-clinical effectiveness of the new drug in treating cancer stem cells in breast, colon, and skin cancers, the scientists will now proceed to study the drug's effect on lung and pancreas cancers, two of the most aggressive types.

colorectal cancer who 2020

They must also complete further ADME-Tox "absorption, distribution, metabolism, excretion and toxicity" studies of the compound's behavior within the organism, a necessary step before carrying out clinical trials. RSC Adv. García-Rubiño, M. Núñez-Carretero, D.

UGR scientists patent an effective drug for treating breast, colon, and skin cancers

Choquesillo-Lazarte, J. García-Ruiz, Yolanda Madrid, J.

colorectal cancer who 2020

Campos, Ana Sánchez, María A. García, Juan A. Oncotarget,5 11 Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission.

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Molecular Testing for Metastatic CRC in 2020

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